Computational drug discovery

Prodrug prediction from SMILES

Submit one to ten molecular structures. The service returns a screening probability and a fixed-scale prodrug-likeness score for every valid molecule.

10SMILES per screening
2Complementary model scores
40Selected Avalon features

Live research tool

Batch molecular screening

Add names for readability, then enter valid SMILES strings.

How to read the output

Two signals, one screening view

Scores support research prioritization. They do not replace experimental, pharmacokinetic, toxicological or clinical validation.

  1. Screening probability
    The ExtraTrees classifier output for the positive prodrug class. It is intentionally described as uncalibrated.
  2. Prodrug-likeness
    The one-class LOF score mapped to a fixed 0 to 100 percentile scale using the training reference distribution.
  3. Rank
    Valid entries are ranked by screening probability while the original input order remains visible in the table.